Mouse tim 4 protein
NettetThe extracellular domain of mouse Tim-4 (aa 22-279) is fused to the N-terminus of the Fc region of human IgG1. Measured by its ability to inhibit anti-CD3-induced proliferation … NettetTim-4 (mouse):Fc (human) (rec.) (TIM4) (#AG-40B-0180) is a low endotoxin and high purity recombinant protein produced in HEK293 cells. It is important for immune …
Mouse tim 4 protein
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Nettet27. sep. 2005 · UniProt Q6U7R4 · TIMD4_MOUSE Protein T-cell immunoglobulin and mucin domain-containing protein 4 Gene Timd4 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 343 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History … NettetClone REA999 recognizes the mouse antigen TIM-4, which is also known as T cell immunoglobulin and mucin domain-containing protein 4 or spleen, mucin-containing, knockout of lymphotoxin protein (SMUCKLER). TIM-4 is a member of the TIM gene family, which is involved in a variety of immunity related processes including T cell proliferation …
NettetHere, we found that mouse resident peritoneal macrophages expressing Tim4 and MerTK are highly efficient at engulfing apoptotic cells. Neutralizing antibodies against either … NettetTIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain.
NettetThe newly identified TIM family of proteins is associated with regulation of T helper type 1 (T(H)1) and T(H)2 immune responses. TIM-1 is genetically linked to asthma and is a … Nettet24. okt. 2007 · Mouse Tim4 is a type I membrane protein, consisting of a signal sequence and extracellular, transmembrane and cytosolic regions ( Fig. 3a ). To examine how Tim4 enhances the engulfment of...
NettetFigure 1: Specific binding of Tim-4 (mouse):Fc (human) (rec.) (Biotin) (Prod. No. AG-40B-0180B) to phosphatidylserine (PS) is dependend on calcium. Methods: Phosphatidylserine or phosphatidylcholine (at 5µg/ml in methanol) are coated on polystyrene ELISA plate and air-dried overnight.
Nettet>98% pure Tim-4 mouse recombinant ... TIM4; TIMD4; T Cell Immunoglobulin and Mucin Domain-containing Protein 4; T Cell Membrane Protein 4: Gene Symbol: TIMD4: … bomb in gpoNettetDetects mouse TIM‑1/KIM-1/HAVCR in ELISAs and Western blots. This antibody does not cross-react with recombinant human (rh) TIM‑1, rmTIM-2, or rmTIM-3. Source Monoclonal Rat IgG 2B Clone # 222414 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Mouse myeloma cell line NS0-derived recombinant mouse … bombing range brewing richlandNettet30. aug. 2011 · ab47637 has been referenced in 7 publications. Zheng L et al. Inhibition of TIM-4 protects against cerebral ischaemia-reperfusion injury. J Cell Mol Med 24:1276-1285 (2024). PubMed: 31774937; … gms speditionNettet1. nov. 2024 · T cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a member of the TIM family, was originally identified as a receptor expressed on … bombing of us embassy kenyaNettet15. aug. 2024 · Protein S (ProS) and growth arrest-specific 6 (Gas6) bind to phosphatidylserine (PtdSer) and induce efferocytosis upon binding TAM-family … bombing of us senate 11/7/83NettetClone REA999 recognizes the mouse antigen TIM-4, which is also known as T cell immunoglobulin and mucin domain-containing protein 4 or spleen, mucin-containing, … bombing run go boom videoNettet5. jul. 2016 · T cell immunoglobulin and mucin (TIM)-4 is a protein expressed by APC [24 ... Conversely, TIM-4+ macrophages from CT-treated mice acquired significantly more antigen compared to TIM-4+ macrophages from untreated mice. TIM-4 hi and TIM-4 int DC also acquired significantly more antigen than steady-state TIM-4− DC (Fig 5E and 5F). bombingscience free shipping