Can atorvastatin cause low platelets

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WebNov 16, 2008 · While absolute lymphocyte (p=0.003) and platelet counts (p=0.001) were decreased with atorvastatin treatment, absolute monocyte count increased (p=0.002). On flow-cytometric examination, the expressions of CD14 (p=0.015) and CD19 (p=0.039) on lymphocytes were decreased with atorvastatin. WebMay 19, 2010 · Atorvastatin was discontinued and his platelet counts improved gradually with steroids. He is now established on a different statin with no further episodes of thrombocytopenia. Though a drug challenge was never done, an idiosyncratic reaction to the initial statin seems to be the most likely cause.

Transaminitis: Symptoms, Causes, and Treatment - Healthline

WebRhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. WebMar 1, 2008 · To explore the effect of short-term cholesterol-lowering treatment with atorvastatin on erythrocyte sodium–lithium countertransport (Na+/Li+ ... 140–159 mm Hg and/or diastolic BP, 90–99 mm Hg) and primary hypercholesterolemia low-density lipoprotein (LDL) cholesterol >4.1 mmol/l and triglycerides (TG) <2.8 mmol/l), group B of … fishel coronado

Effect of Statins on Platelet Activation and Function: From ... - PubMed

WebApr 27, 2024 · Thrombocytopenia (low blood platelet count) Weakness, numbness and pain, often in the hands and feet (peripheral neuropathy) ... There is no specific interaction between Crestor and alcohol, but statins in general can cause liver problems, which can be worsened by excessive alcohol consumption. It may be best to check with your doctor … WebSevere internal bleeding: Thrombocytopenia may cause gastrointestinal bleeding or bleeding in your brain. Bleeding into your brain is a life-threatening issue. ... You might not need treatment if a low platelet count isn’t causing significant issues. Often, healthcare providers can improve platelet counts by treating the underlying cause. ... WebAim: To investigate the effects of statins on mean platelet volume (MPV) which is a simple measure of platelet activation volume in patients who have been prescribed statins. … fishel company florida

Medications That Cause Low Platelet Count Healthfully

Statins Side Effects: Pain, Inflammation, and More - WebMD

WebMar 24, 2024 · Alcohol can damage your bone marrow and cause it to make fewer platelets than normal. Certain foods or herbs may raise your risk of low platelet counts. These include English walnuts and sesame seeds. Using tobacco products may cause your body to make fewer platelets than normal. WebJan 25, 2024 · This study was a milestone in providing a mechanism for the pleiotropic effect of statins that can lead to early clinical benefits. Statins may also affect platelet energy metabolism. Vevera et al. reported a reduction of mitochondrial platelet respiration in a rat model treated with rosuvastatin and atorvastatin. fishel contractorsWebMar 25, 2013 · However, for some, the platelet count can remain at a safe level when the treatments are discontinued. In a study of 31 chronic ITP patients taking TPO agents in a single practice, nine were able to discontinue the treatments and retain their elevated platelet count. ... This case reminds us that some of the most popular drugs can cause … canada cartage ownership

"WebLow platelet count, known as thrombocytopenia, can be a side effect of certain medications. Is This an Emergency? If you are experiencing serious medical symptoms, … " - Can atorvastatin cause low platelets

Can atorvastatin cause low platelets

Side Effects of Statin Drugs for Cholesterol - Verywell Health

WebOct 17, 1998 · Serial blood analysis showed stable platelet counts. 2 months before admission, the patient had started atorvastatin 10 mg per day because of inadequate … WebApr 1, 2024 · Descriptions. Atorvastatin is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel ...

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WebFeb 1, 2005 · This hypothesis was supported by an in vitro study, which demonstrated that atorvastatin dose-dependently inhibited collagen-induced CD40L expression; it should be noted that inhibition of platelet CD40L expression was observed at atorvastatin concentrations as low as 0.1 μmol/L, which may be achieved in the peripheral … WebMar 15, 2024 · Atorvastatin increases EPCs and thrombopoiesis in corticosteroid-resistant ITP. (A) In the BM of corticosteroid-resistant ITP, decreased numbers and dysfunctional EPCs lead to platelet …

WebRash. Low levels of blood platelets. Less common side effects you may have with statins are: Nausea. Hair loss. Pins and needles sensations, such as pricking, numbness, or tingling on your skin ... WebSide effects can vary between different statins, but common side effects include: headache. dizziness. feeling sick. feeling unusually tired or physically weak. digestive system problems, such as constipation, diarrhoea , indigestion or farting. muscle pain. sleep problems. low blood platelet count.

WebJun 14, 2024 · The NHS explains that thrombocytopenia is a shortage of platelets. It states: “If you don't have a normal number of platelets, doctors say that you are …

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WebNov 30, 2024 · Certain drugs have been shown to directly mediate an antibody-independent platelet apoptosis by causing Ca+2 signaling, mitochondrial depolarization, and phosphatidylserine exposure in platelets (). 4,5 Although these findings sound interesting, not all patients treated with these drugs experience some degree of … canada child benefit back paymentWebAnswered by Dr. Robert Grindstaff: Yes: one of the known side effects is decreased platelets "can the use of lipitor (atorvastatin) lower the platelet count?" U.S. doctors … canada child benefit age limitWebOct 16, 2024 · Many things can cause elevated liver enzymes, which is known as transaminitis. ... statins, such as atorvastatin (Lipitor) and lovastatin (Mevacor, Altocor) ... low platelet count; canada child benefit application form rc66schWebJul 8, 2011 · Stroke is a major cause of morbidity and one of the leading causes of death worldwide [].Atherothrombosis and inflammation play important roles in the pathogenesis of acute ischemic stroke [2–4].A previous study demonstrates that platelet activity, measured by CD62P and CD63 expressions on platelets, are increased after acute ischemic … fishel dental laboratoryWebOct 4, 2024 · Many conditions can cause a decrease in the production of platelets. These conditions often prevent bone marrow from making platelets. Certain viruses, poor nutrition, and heavy alcohol use can … canada child benefit call numberWebWhen medicines or drugs are the causes of a low platelet count, it is called drug-induced thrombocytopenia. Causes Drug-induced thrombocytopenia occurs when certain … canada cell phone samsung a5WebThe risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. Liver damage Amlodipine-atorvastatin (Caduet) The statin component decreases LDL and … The same heart-healthy lifestyle changes that can lower your cholesterol can help … A high blood cholesterol level increases your risk of coronary artery disease. … When arcus senilis occurs in older adults, it isn't related to high cholesterol. … Olive oil provides monounsaturated fat, which lowers total cholesterol and low … canada child benefit contact phone number